Black Seed Oil for Rheumatoid Arthritis

rheumatoid damage

Black Seed Oil for Rheumatoid Arthritis

Black seed oil and its components are showing promise as therapy for a range of autoimmune diseases including rheumatoid arthritis.

Rheumatoid arthritis is a disease in which the bodies immune system creates a response against its own connective tissues. The abnormal immune response results in inflammation and destruction of the tissues.

The connective tissue affected in rheumatoid arthritis is commonly in the joints however it  can affect other parts of the body including the lungs, skin, heart. Traditionally rheumatoid arthritis was treated with steroids to dampen the inflammation and suppress the abnormal immune response.

Long term control of the disease often requires use of dugs which modify the immune system (immunomodulator therapy). Although these drugs help to reduce flare-ups they come with potential side effects including liver damage, infections and blood disorders.

Black seed oil possesses many properties which make is a potential natural therapy for patients with rheumatoid arthritis: –

  • Analgesic (pain relieving)
  • Anti-inflammatory
  • Immunomodulator (regulates immune system)
  • Hepato / reno – protective (protects liver / kidneys)
black seed oil, just 1 capsule taken twice a day was effective in reducing inflammatory markers, DAS-28 score (a measure of disease activity in rheumatoid arthritis) and an improved number of swollen joints compared with baseline and placebo groups
Studies examining the effects of black seed oil on rheumatoid arthritis…

A lab based study examined the effects of thymoquinone (volatile oil of black seed oil)  in an animal model of rheumatoid arthritis. [1]
The results of this study confirmed that clinical and radiological signs of rheumatoid arthritis were suppressed in arthritis in rats who took the extract of black seed oil.

A randomised placebo controlled study on patients suffering from rheumatoid arthritis [2]
The beneficial effects of black seed oil on all the symptoms of rheumatoid arthritis was confirmed. The study found that the rheumatoid arthritis disease activity score improved in group of patients taking black seed oil. The number of swollen joints and the duration of morning stiffness all improved significantly more in the group taking  Nigella sativa oil compared to placebo.

A study which aimed to examine the molecular mechanisms which make black seed oil extract thymoquinone protective against rheumatoid arthritis [3]
The study examined isolated human rheumatoid arthritis fibroblast-like synoviocytes (joint lining cells) and a rat adjuvant-induced arthritis model of rheumatoid arthritis.

The main aim of the study was to investigate the influence of thymoquinone on the major signalling pathways involved in disease  changes in rheumatoid arthritis. The study concluded that thymoquinone abolishes a number of factors known to be involved in rheumatoid arthritis and that it is a clinically valuable agent in the prevention of joint diseases.

Additionally, black seed oil is proven in many studies to protect the liver and the kidneys  from damage, this effect could prove protective for those taking conventional drugs for rheumatoid arthritis.

1. Tekeoglu I, Dogan A, Ediz L, et al.  Effects of thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models. Phytother Res. 2007 Sep;21(9):895-7.


2. Gheita TA, Kenawy SA. Effectiveness of Nigella sativa oil in the management of rheumatoid arthritis patients: a placebo controlled study. Phytother Res. 2012 Aug;26(8):1246-8.


3. Vaillancourt F, Silva P, Shi Q, et al. Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis. J Cell Biochem. 2011 Jan;112(1):107-17. doi: 10.1002/jcb.22884.

Related Post

8 thoughts on “Black Seed Oil for Rheumatoid Arthritis

    • nabiblackseed says:

      Dear James

      It depends if the disease is active or stable. If disease is active take one 5ml spoon 30 minutes before each meal (3 or 4 times a day). Once the condition settles then reduce this down to a daily maintenance of one spoon say in the morning and one before bed.

      Kind regards
      Team @ NabiBlackseedOil

  1. merzeen says:

    I like to know I have been taking back seedoil for NEARLY for a month but nothing changes still my weight is same and still I have pain in my body! I have been taking the capusul and the oil with honey each morning with empty stomach and night before going to bed

    • nabiblackseed says:

      Dear Merzeen
      It must be combined with increased exercise, the black seed oil benefits for weight loss have been found when tested in groups of patients undergoing an exercise regime. The groups taking Nigella sativa oil loose more weight, likely because of increased metabolism. Simply taking black seed oil alone is not going to make you loose weight.
      Kind regards
      Team @

  2. muhammad awais hussain says:

    I am sufring from rhumatide since 2013 pleas tell me is black seed benificeal for me what dose shoud i take

    • nabiblackseed says:

      Dear Muhammad
      It depends on how active the disease is and your body weight. Black seed oil is increasingly being proven to be beneficial for Rheumatoid arthritis
      This paper is hot off the press:
      Try 1 x 5ml spoon in the morning before breakfast with honey and increase if the disease becomes more active to 2 or 3 spoons per day.
      Kind regards
      Team @ Nabi Blackseed

Leave a Reply

Your email address will not be published. Required fields are marked *